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ARUK200282

Chemical Structure : ARUK200282

CAS No.:

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ARUK200282 (ARUK 200282)

Catalog No.: PC-20866Not For Human Use, Lab Use Only.

ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ. has broad selectivity against lipid and protein kinases.

Physicochemical Properties

M.Wt 378.86
Formula C21H19ClN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

CC1=CC=C(N2C=CC3=C(NC4=CC=C(OC)C(Cl)=C4)N=CN=C32)C=C1C

References

1. Henriëtte M G Willems, et al. RSC Med Chem. 2023 Apr 17;14(5):934-946.

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