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ARUK2002821

Chemical Structure : ARUK2002821

CAS No.:

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ARUK2002821 (ARUK 2002821)

Catalog No.: PC-21275Not For Human Use, Lab Use Only.

ARUK2002821 is a potent, selective PI5P4Kα inhibitor with pIC50 of 8.0, >1000-fold selective over PI5P4Kγ.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ARUK2002821 is a potent, selective PI5P4Kα inhibitor with pIC50 of 8.0, >1000-fold selective over PI5P4Kγ.

Physicochemical Properties

M.Wt 378.86
Formula C21H19ClN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3-chloro-4-methoxyphenyl)-7-(3,4-dimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

References

1. Willems H. M. G. Edwards S. Boffey H. K. Chawner S. J. Green C. Romero T. Winpenny D. Skidmore J. Clarke J. H. Andrews S. P. RSC Med. Chem. 2023;14:934–946.

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