ASP4345 | D1R PAM | Probechem Biochemicals

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Chemical Structure : ASP4345

ASP4345 (ASP-4345)

Catalog No.: PC-49304Not For Human Use, Lab Use Only.

ASP4345 (ASP-4345) is a potent, selective positive allosteric modulator of the dopamine type 1 (D1) receptor that selectively binds to, and enhances the activity of, D1 receptors.

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Biological Activity

ASP4345 (ASP-4345) is a potent, selective positive allosteric modulator of the dopamine type 1 (D1) receptor that selectively binds to, and enhances the activity of, D1 receptors.

Physicochemical Properties

M.Wt	438.791
Formula	C19H14ClF3N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(5-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)-N-methyl-N-((5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)methyl)acetamide

References

1. Amit Desai, et al. Clin Pharmacokinet. 2021 Jan;60(1):79-88.

2. Desai A, et al. Neuropsychopharmacology. 2021 May;46(6):1145-1151.

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ASP4345 (ASP-4345)

Biological Activity

Physicochemical Properties

References

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