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AWE402

Chemical Structure : AWE402

CAS No.: 1440650-66-7

AWE402 (AWE-402)

Catalog No.: PC-49603Not For Human Use, Lab Use Only.

AWE402 (AWE-402) is a small molecule inhibitor targeting M. tuberculosis cytochrome bcc-aa3 of the electron transport chain (ETC), shows MIC value of 5 nM activity against Mycobacterium tuberculosis H37Rv.

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    Biological Activity

    AWE402 (AWE-402) is a small molecule inhibitor targeting M. tuberculosis cytochrome bcc-aa3 of the electron transport chain (ETC), shows MIC value of 5 nM activity against Mycobacterium tuberculosis H37Rv.

    Physicochemical Properties

    M.Wt 389.43
    Formula C23H20FN3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(4-(4-fluorophenoxy)benzyl)-2,6-dimethylimidazo[1,2-a]pyridine-3-carboxamide

    References

    1. Moraski, G. C.et al. ACS Med. Chem. Lett. 2013, 4, 675– 679

    2. Patent WO2017103615A1

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