AWE402 | Cyt bcc-aa3 inhibitor | Probechem Biochemicals

Chemical Structure : AWE402

AWE402 (AWE-402)

Catalog No.: PC-49603Not For Human Use, Lab Use Only.

AWE402 (AWE-402) is a small molecule inhibitor targeting M. tuberculosis cytochrome bcc-aa3 of the electron transport chain (ETC), shows MIC value of 5 nM activity against Mycobacterium tuberculosis H37Rv.

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Biological Activity

AWE402 (AWE-402) is a small molecule inhibitor targeting M. tuberculosis cytochrome bcc-aa3 of the electron transport chain (ETC), shows MIC value of 5 nM activity against Mycobacterium tuberculosis H37Rv.

Physicochemical Properties

M.Wt	389.43
Formula	C23H20FN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(4-fluorophenoxy)benzyl)-2,6-dimethylimidazo[1,2-a]pyridine-3-carboxamide

References

1. Moraski, G. C.et al. ACS Med. Chem. Lett. 2013, 4, 675– 679

2. Patent WO2017103615A1

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AWE402 (AWE-402)

Biological Activity

Physicochemical Properties

References

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