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Chemical Structure : AX-15836
Catalog No.: PC-70300Not For Human Use, Lab Use Only.
A potent, highly selective ERK5 inhibitor with IC50 of 8 nM.
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A potent, highly selective ERK5 inhibitor with IC50 of 8 nM; shows little affinity for BRD4 (Kd=3.6 uM); clearly inhibits the EGF-stimulated, phosphorylated form of ERK5 in HeLa cells.
| M.Wt | 648.783 | |
| Formula | C32H40N8O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lin EC, et al. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11865-11870.
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