| Cat. No. |
Product Name |
Information |
| PC-22330 |
Ravoxertinib
ERK1/2 inhibitor
|
Ravoxertinib (GDC-0994) is potent, selective and orally active ERK kinase inhibitor with IC50 of 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively. |
| PC-20223 |
Ulixertinib hydrochloride
ERK1/2 inhibitor
|
Ulixertinib hydrochloride (BVD-523) is a potent, selective, reversible, ATP-competitive ERK1/2 inhibitor with Ki of 0.3/0.04 nM, respectively. |
| PC-20222 |
Ulixertinib
ERK1/2 inhibitor
|
BVD-523 (Ulixertinib) is a potent, selective, reversible, ATP-competitive ERK1/2 inhibitor with Ki of 0.3/0.04 nM, respectively. |
| PC-38646 |
Edaxeterkib
ERK inhibitor
|
Edaxeterkib is a small molecule inhibitor of extracellular signal-regulated kinase (ERK). |
| PC-38371 |
Rineterkib
ERK1/2 inhibitor
|
Rineterkib (LTT462) is a small molecule inhibitor of ERK1/2, has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models. |
| PC-72428 |
ASN007
ERK inhibitor
|
ASN007 (ASN-007) is a potent, selective, orally bioavailable ERK1/2 inhibitor with IC50 of 2 nM against both. |
| PC-72401 |
ASTX029
ERK1/2 inhibitor
|
Beroterkib (ASTX029, ASTX-029) is a highly potent, selective dual-mechanism ERK inhibitor with IC50 of <3 nM for ERK1/2, inhibits both ERK catalytic activity and the phosphorylation of ERK by MEK. |
| PC-72142 |
XMD8-85
ERK5 inhibitor
|
XMD8-85 is a selective ERK5 inhibitor with IC50 of 87 nM in enzyme assay. |
| PC-72141 |
JWG-071
ERK5 inhibitor
|
JWG-071 is a selective Erk5 inhibitor (IC50<20 nM) with reduced Brd4/BET inhibitory activity. |
| PC-72106 |
SF-3-030
ERK1/2 inhibitor
|
SF-3-030 is a novel ATP-dependent/catalytic site inhibitor of ERK1/2, inhibits A375 cell viability with IC50 of 4.9 uM. |
| PC-35813 |
CC-90003
ERK1/2 inhibitor
|
CC-90003 (CC90003) is a potent and selective, covalent ERK1/2 inhibitor with IC50 of 10-20 nM, demonstrates excellent selectivity in a 258-kinase biochemical assay panel. |
| PC-35338 |
AZ6197
ERK1/2 inhibitor
|
AZ6197 (AZ-6197) is a potent, selective, reversible inhibitor of ERK1/2 with IC50 of <0.3 nM (ERK2), inhibits pERK/pRSK with IC50 of 12/62 nM in A375 cells, respectively. |
