| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-72141 |
JWG-071
|
2250323-50-1 |
JWG-071 is a selective Erk5 inhibitor (IC50<20 nM) with reduced Brd4/BET inhibitory activity. |
| PC-35813 |
CC-90003
|
1621999-82-3 |
CC-90003 (CC90003) is a potent and selective, covalent ERK1/2 inhibitor with IC50 of 10-20 nM, demonstrates excellent selectivity in a 258-kinase biochemical assay panel. |
| PC-35332 |
BAY-885
|
2307249-33-6 |
BAY-885 (BAY885) is a highly potent, selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM, shows high selectivity over a panel of 357 kinases (Eurofins panel). |
| PC-63271 |
AZD0364
|
2097416-76-5 |
Tizaterkib (AZD0364) is a potent, selective, ATP competitive, orally active ERK1/2 inhibitor with IC50 of 0.66 nM in ERK2 biochemical assay, binds similarly to ERK1 and ERK2 with Ki of 3.9 and 3.8 nM. |
| PC-62596 |
MK-8353 hydrochloride
|
1951448-73-9 |
MK-8353 hydrochloride (SCH-900353) is a highly potent, orally bioavailable, dual-specificity ERK1/2 inhibitor with IC50 of 23.0/8.8 nM, respectively. |
| PC-62595 |
MK-8353
|
1184173-73-6 |
MK-8353 (SCH-900353) is a highly potent, orally bioavailable, dual-specificity ERK1/2 inhibitor with IC50 of 23.0/8.8 nM, respectively. |
| PC-61978 |
KO-947
|
1695533-89-1 |
KO-947 (KO947) is a potent and selective inhibitor of ERK1/2 kinase in biochemical, cellular and in vivo antitumor activity assays. |
