Cat. No. |
Product Name |
Information |
PC-20222 |
Ulixertinib
ERK inhibitor
|
BVD-523 (Ulixertinib) is a potent, selective, reversible, ATP-competitive ERK1/2 inhibitor with Ki of 0.3/0.04 nM, respectively. |
PC-38646 |
Edaxeterkib
ERK inhibitor
|
Edaxeterkib is a small molecule inhibitor of extracellular signal-regulated kinase (ERK). |
PC-38371 |
Rineterkib
ERK1/2 inhibitor
|
Rineterkib (LTT462) is a small molecule inhibitor of ERK1/2, has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models. |
PC-72142 |
XMD8-85
ERK5 inhibitor
|
XMD8-85 is a selective ERK5 inhibitor with IC50 of 87 nM in enzyme assay. |
PC-72106 |
SF-3-030
ERK inhibitor
|
SF-3-030 is a novel ATP-dependent/catalytic site inhibitor of ERK1/2, inhibits A375 cell viability with IC50 of 4.9 uM. |
PC-35338 |
AZ6197
|
AZ6197 (AZ-6197) is a potent, selective, reversible inhibitor of ERK1/2 with IC50 of <0.3 nM (ERK2), inhibits pERK/pRSK with IC50 of 12/62 nM in A375 cells, respectively. |
PC-63537 |
Astex ERK inhibitor X
|
Astex ERK inhibitor X is a novel potent ERK1/2 inhibitor that inhibits ERK catalytic activity with IC50 of 3 nM in TRK kinase assays. |
PC-70300 |
AX-15836
|
A potent, highly selective ERK5 inhibitor with IC50 of 8 nM. |
PC-45672 |
Tauroursodeoxycholic acid sodium
|
Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate. |
PC-45562 |
DEL-22379
|
A small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation. |
PC-43855 |
VX-11e
|
A potent, selective, and orally bioavailable inhibitor of ERK2 with Ki of <2 nM. |
PC-45868 |
SCH-772984
|
A novel potent and selective inhibitor of ERK1/ERK2 with IC50 of 4 nM/1 nM, respectively. |