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Cat. No. Product Name Information
PC-20222

Ulixertinib

ERK inhibitor

BVD-523 (Ulixertinib) is a potent, selective, reversible, ATP-competitive ERK1/2 inhibitor with Ki of 0.3/0.04 nM, respectively.
PC-38646

Edaxeterkib

ERK inhibitor

Edaxeterkib is a small molecule inhibitor of extracellular signal-regulated kinase (ERK).
PC-38371

Rineterkib

ERK1/2 inhibitor

Rineterkib (LTT462) is a small molecule inhibitor of ERK1/2, has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models.
PC-72142

XMD8-85

ERK5 inhibitor

XMD8-85 is a selective ERK5 inhibitor with IC50 of 87 nM in enzyme assay.
PC-72106

SF-3-030

ERK inhibitor

SF-3-030 is a novel ATP-dependent/catalytic site inhibitor of ERK1/2, inhibits A375 cell viability with IC50 of 4.9 uM.
PC-35338

AZ6197

AZ6197 (AZ-6197) is a potent, selective, reversible inhibitor of ERK1/2 with IC50 of <0.3 nM (ERK2), inhibits pERK/pRSK with IC50 of 12/62 nM in A375 cells, respectively.
PC-63537

Astex ERK inhibitor X

Astex ERK inhibitor X is a novel potent ERK1/2 inhibitor that inhibits ERK catalytic activity with IC50 of 3 nM in TRK kinase assays.
PC-70300

AX-15836

A potent, highly selective ERK5 inhibitor with IC50 of 8 nM.
PC-45672

Tauroursodeoxycholic acid sodium

Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate.
PC-45562

DEL-22379

A small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation.
PC-43855

VX-11e

A potent, selective, and orally bioavailable inhibitor of ERK2 with Ki of <2 nM.
PC-45868

SCH-772984

A novel potent and selective inhibitor of ERK1/ERK2 with IC50 of 4 nM/1 nM, respectively.

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