Pluripotin |CAS:839707-37-8 Probechem Biochemicals

Chemical Structure : Pluripotin

CAS No.: 839707-37-8

Pluripotin (SC-1;SC1;SC 1)

Catalog No.: PC-42663Not For Human Use, Lab Use Only.

Pluripotin(SC1) is a small molecule that can maintain the self-renewal of mESC (murine embryonic stem cells) in the absence of feeder cells and exogenous factors.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$148	In stock
25 mg	$258	In stock
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Biological Activity

Pluripotin(SC1) is a small molecule that can maintain the self-renewal of mESC (murine embryonic stem cells) in the absence of feeder cells and exogenous factors.
Pluripotin works through dual inhibition of RasGAP and ERK1.
Pluripotin maintains the undifferentiated phenotype of mES cells with EC50 of 1 uM, and shows low cellular toxicity (>30 uM).

Physicochemical Properties

M.Wt	550.535
Formula	C27H25F3N8O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 33 mg/mL
Chemical Name/SMILES	Benzamide, N-[3-[7-[(1,3-dimethyl-1H-pyrazol-5-yl)amino]-1,4-dihydro-1-methyl-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)-

References

1. Chen S, et al. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17266-71.

2. Yang W, et al. Stem Cells. 2009 Feb;27(2):383-9.

3. Pieters T, et al. Stem Cell Rev. 2012 Sep;8(3):768-78.

Pluripotin (SC-1;SC1;SC 1)

Biological Activity

Physicochemical Properties

References

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