Cat. No. |
Product Name |
Information |
PC-22946 |
EI-52
ERK-MYD88 inhibitor
|
EI-52 is a small molecule inhibitor of ERK-MYD88 interaction, binds ERK1/2 (Kd=4.3/2.1 uM), inhibits ERK1/2-MYD88 interaction with IC50 of 3.1/14.7 uM in HTRF assays, induces cancer cell death. |
PC-22834 |
XMD8-92
ERK5 inhibitor
|
XMD8-92 a specific small-molecule inhibitor of Big mitogen-activated protein kinase 1 (BMK1, ERK5) with Kd of 80 nM, IC50 of 1.5 uM in cell-free assays. |
PC-22330 |
Ravoxertinib
ERK inhibitor
|
Ravoxertinib (GDC-0994) is potent, selective and orally active ERK kinase inhibitor with IC50 of 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively. |