Chemical Structure : VX-11e
CAS No.:
896720-20-0
VX-11e
(VX11e)
Catalog No. : PC-43855Not For Human Use, Lab Use Only.
VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK2 with Ki of <2 nM.
Packing Price Stock Quantity 5 mg $78 In stock 0 1 2 3 4 5 10 mg $118 In stock 0 1 2 3 4 5 25 mg $198 In stock 0 1 2 3 4 5 50 mg $328 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4385501
Biological Activity
VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK2 with Ki of <2 nM.
Physicochemical Properties
M.Wt
500.3523
Formula
C24H20Cl2FN5O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1H-Pyrrole-2-carboxamide, 4-[2-[(2-chloro-4-fluorophenyl)amino]-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-
References
1. Aronov AM, et al. J Med Chem
2. Krepler C, et al. Clin Cancer Res
3. Guo QS, et al. Sci Rep
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