Chemical Structure : DEL-22379
CAS No.: 181223-80-3
Catalog No.: PC-45562Not For Human Use, Lab Use Only.
DEL-22379 (DEL22379) is a small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation.
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DEL-22379 (DEL22379) is a small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation.
DEL-22379 prevents tumorigenesis by RAS-ERK pathway oncogenes.
M.Wt | 444.5255 | |
Formula | C26H28N4O3 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 30 mg/mL |
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Chemical Name/SMILES |
1-Piperidinepropanamide, N-[2,3-dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]- |
1. Herrero A, et al. Cancer Cell. 2015 Aug 10;28(2):170-82.
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