DEL-22379 |CAS:181223-80-3 Probechem Biochemicals

Chemical Structure : DEL-22379

CAS No.: 181223-80-3

DEL-22379 (DEL22379, DEL 22379)

Catalog No.: PC-45562Not For Human Use, Lab Use Only.

DEL-22379 (DEL22379) is a small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation.

Packing	Price	Stock
5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$198	In stock
50 mg	$328	In stock
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Biological Activity

DEL-22379 (DEL22379) is a small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation.
DEL-22379 prevents tumorigenesis by RAS-ERK pathway oncogenes.

Physicochemical Properties

M.Wt	444.5255
Formula	C26H28N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 30 mg/mL
Chemical Name/SMILES	1-Piperidinepropanamide, N-[2,3-dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-

References

1. Herrero A, et al. Cancer Cell. 2015 Aug 10;28(2):170-82.

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DEL-22379 (DEL22379, DEL 22379)

Biological Activity

Physicochemical Properties

References

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