Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Ras-Raf-MAPK-ERK Pathway-ERK-Rineterkib
Rineterkib

Chemical Structure : Rineterkib

CAS No.: 1715025-32-3

Rineterkib (LTT462, LTT-462)

Catalog No.: PC-38371Not For Human Use, Lab Use Only.

Rineterkib (LTT462) is a small molecule inhibitor of ERK1/2, has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models.

Packing Price Stock Quantity
5 mg $198 In stock
10 mg $298 In stock
25 mg $498 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Rineterkib (LTT462) is a small molecule inhibitor of ERK1/2, has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models.
Rineterkib (LTT462) significantly reduces the tumor volume in the Calu-6 human NSCLC subcutaneous tumor xenograft model in mice.

Physicochemical Properties

M.Wt 578.434
Formula C26H27BrF3N5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(3-amino-6-((1S,3S,4S)-3-fluoro-4-hydroxycyclohexyl)pyrazin-2-yl)-N-((S)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl)-2-fluorobenzamide

References

1. Asaf Maoz, et al. Expert Opin Emerg Drugs. 2019 Dec;24(4):239-253.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: