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Chemical Structure : Rineterkib
CAS No.: 1715025-32-3
Catalog No.: PC-38371Not For Human Use, Lab Use Only.
Rineterkib (LTT462) is a small molecule inhibitor of ERK1/2, has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Rineterkib (LTT462) is a small molecule inhibitor of ERK1/2, has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models.
Rineterkib (LTT462) significantly reduces the tumor volume in the Calu-6 human NSCLC subcutaneous tumor xenograft model in mice.
| M.Wt | 578.434 | |
| Formula | C26H27BrF3N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-(3-amino-6-((1S,3S,4S)-3-fluoro-4-hydroxycyclohexyl)pyrazin-2-yl)-N-((S)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl)-2-fluorobenzamide |
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1. Asaf Maoz, et al. Expert Opin Emerg Drugs. 2019 Dec;24(4):239-253.
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