Chemical Structure : AXC-715 trihydrochloride
CAS No.:
2479276-17-8
AXC-715 trihydrochloride
(AXC715, T785)
Catalog No.: PC-26697Not For Human Use, Lab Use Only.
AXC-715 (T785) trihydrochloride is a small-molecule TLR7 agonist, elicits broad-spectrum antiviral effects, stabilizes TLR7 receptor dimerization to inhibit viral replication.
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| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $428 | In stock | |
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Purity & Documentation Purity:
>98% (HPLC)
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Biological Activity
AXC-715 (T785) trihydrochloride is a small-molecule TLR7 agonist, elicits broad-spectrum antiviral effects, stabilizes TLR7 receptor dimerization to inhibit viral replication.
AXC-715 exhibits direct binding affinity to TLR7 protein, promotes and stabilizes TLR7 dimer formation.
AXC-715 activates NF-κB signaling via a p65-dependent mechanism.
AXC-715 inhibits pseudorabies virus (PRV) and vesicular stomatitis virus (VSV) replication in vitro.
AXC-715 suppresses viral replication in a strictly TLR7-dependent manner, specifically impairing viral replication, distinct from adsorption, entry, assembly, or release processes.
Physicochemical Properties
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M.Wt
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420.81
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Formula
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C18H28Cl3N5
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine trihydrochloride
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References
1. Patent WO2020168017A1.
2. Chen Yao, et al. Microorganisms. 2026 Apr 11;14(4):862.
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