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Chemical Structure : AZ10606120 dihydrochloride
CAS No.: 607378-18-7
Catalog No.: PC-63426Not For Human Use, Lab Use Only.
AZ10606120 dihydrochloride is a potent, specific P2X7 receptor antagonist with Kd of 1.4 and 19 nM at human and rat P2X7 receptors respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | Get quote |
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AZ10606120 dihydrochloride is a potent, specific P2X7 receptor antagonist with Kd of 1.4 and 19 nM at human and rat P2X7 receptors respectively.
AZ10606120 strongly inhibits tumor growth in B16-inoculated C57Bl/6 mice.
| M.Wt | 495.489 | |
| Formula | C25H36Cl2N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride |
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1. Yan Z, et al. J Neurosci. 2010 Oct 20;30(42):14213-24.
2. Mohammed A, et al. Oncotarget. 2017 Oct 26;8(58):97822-97834.
3. Adinolfi E, et al. Cancer Res. 2012 Jun 15;72(12):2957-69.
4. Michel AD, et al. Br J Pharmacol. 2008 Feb;153(4):737-50.
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