Chemical Structure : AZ10606120 dihydrochloride
CAS No.:
607378-18-7
AZ10606120 dihydrochloride
(AZ 10606120, AZ-10606120)
Catalog No. : PC-63426Not For Human Use, Lab Use Only.
AZ10606120 dihydrochloride is a potent, specific P2X7 receptor antagonist with Kd of 1.4 and 19 nM at human and rat P2X7 receptors respectively.
Packing Price Stock Quantity 5 mg $128 In stock 0 1 2 3 4 5 10 mg $188 In stock 0 1 2 3 4 5 25 mg $328 In stock 0 1 2 3 4 5 50 mg $528 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6342601
Biological Activity
AZ10606120 dihydrochloride is a potent, specific P2X7 receptor antagonist with Kd of 1.4 and 19 nM at human and rat P2X7 receptors respectively.
Physicochemical Properties
M.Wt
495.489
Formula
C25H36Cl2N4O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride
References
1. Yan Z, et al. J Neurosci.
2. Mohammed A, et al. Oncotarget.
3. Adinolfi E, et al. Cancer Res
4. Michel AD, et al. Br J Pharmacol.
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