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Chemical Structure : AZ 13381758
Catalog No.: PC-60616Not For Human Use, Lab Use Only.
A potent, small molecule CXCR2 inhibitor with IC50 of 26 nM and 30 nM for mCXCR2 and hCXCR2, respectively.
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AZ 13381758 is a potent, small molecule CXCR2 inhibitor with IC50 of 26 nM and 30 nM for mCXCR2 and hCXCR2, respectively.
AZ 13381758 inhibits the growth and metastatic potential pancreatic ductal adenocarcinoma, enhances sensitivity to anti-PD1 immunotherapy in vivo; chemical analog of AZD 5069.
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| Appearance | Solid | |
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10 mM in DMSO |
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