Chemical Structure : AZ3451
CAS No.: 2100284-59-9
Catalog No.: PC-60321Not For Human Use, Lab Use Only.
AZ3451 (AZ-3451) is a potent, and selective PAR2 antagonist with Kd of 13.5 nM, shows excellent selectivity over PAR1 and PAR4 (>50 uM).
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AZ3451 (AZ-3451) is a potent, and selective PAR2 antagonist with Kd of 13.5 nM, shows excellent selectivity over PAR1 and PAR4 (>50 uM).
| M.Wt | 571.475 | |
| Formula | C30H27BrN4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-2-(6-bromobenzo[d][1,3]dioxol-5-yl)-N-(4-cyanophenyl)-1-(1-cyclohexylethyl)-1H-benzo[d]imidazole-5-carboxamide |
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1. Cheng RKY, et al. Nature. 2017 May 4;545(7652):112-115.

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