Chemical Structure : AZD-7762
CAS No.: 860352-01-8
Catalog No.: PC-42769Not For Human Use, Lab Use Only.
AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM, also is a potent and selective VRK2 (vaccine-associated kinase 2) inhibitor with IC50 of 9.957 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $58 | In stock | |
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM, also is a potent and selective VRK2 (vaccine-associated kinase 2) inhibitor with IC50 of 9.957 nM.
AZD-7762 shows less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.
AZD-7762 enhances the radiosensitivity of mutated p53 tumor cell lines and HT29 xenografts.
| M.Wt | 362.4218 | |
| Formula | C17H19FN4O2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Thiophenecarboxamide, 3-[(aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl- |
|
1. Zabludoff SD, et al. Mol Cancer Ther. 2008 Sep;7(9):2955-66.
2. Mitchell JB, et al. Clin Cancer Res. 2010 Apr 1;16(7):2076-84.
3. Morgan MA, et al. Cancer Res. 2010 Jun 15;70(12):4972-81.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright