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Cat. No. Product Name CAS No. Information
PC-63128

BAY-1816032

1891087-61-8 BAY-1816032 (BAY1816032) is a highly potent, selective, orally active BUB1 mitotic checkpoint serine/threonine kinase with IC50 of 7 nM, displays excellent selectivity on a panel of 395 kinases.
PC-60310

GNE-900

1200126-26-6 GNE-900 (GNE900) is a potent, selective, ATP-competitive, and orally bioavailable Chk1 inhibitor with IC50 of <1 nM.
PC-60276

GDC-0575

1196541-47-5 GDC-0575 (ARRY-575, RG-7741) is a potent, selective and orally bioavailable Chk1 inhibitor with IC50 of 1.2 nM.
PC-45427

Prexasertib

1234015-52-1 Prexasertib (LY-2606368) is a potent, selective, ATP-competitive inhibitor of CHK1 with Ki of 0.9 nM.
PC-42769

AZD-7762

860352-01-8 AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM.
PC-45574

CCT-245737

1489389-18-5 CCT-245737 (SRA-737) is a highly potent, selective, ATP-competitive inhibitor of Chk1 with IC50 of 1.3 nM.
PC-35602

PF-00477736

952021-60-2 PF-00477736 (PF-477736) is a potent, selective, ATP-competitive inhibitor of Chk1 with Ki of 0.49 nM, also inhibits Chk2 (Ki=47 nM) and poorly inhibits CDK1 activity (Ki=9.9 uM).

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