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AZD0022

Chemical Structure : AZD0022

CAS No.: 2958627-18-2

AZD0022 (AZD-0022 )

Catalog No.: PC-24666Not For Human Use, Lab Use Only.

AZD0022 is a potent, selective and orally bioavailable inhibitor of KRAS G12D.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AZD0022 is a potent, selective and orally bioavailable inhibitor of KRAS G12D.

Physicochemical Properties

M.Wt 614.65
Formula C34H30F4N6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Naphthalenamine, 4-[4-(3,8-diazabicyclo[3.2.1]oct-6-en-3-yl)-6,8-difluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]-7-quinazolinyl]-5-ethynyl-6-fluoro-, (4R)-

References

1. Kevin Beaumont, et al. Cancer Res (2025) 85 (8_Supplement_1): 841.

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