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Chemical Structure : AZD1152-HQPA
CAS No.: 722544-51-6
Catalog No.: PC-42340Not For Human Use, Lab Use Only.
The active product of AZD1152, a potent, selective inhibitor of Aurora B kinase with IC50 of 0.37 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $117.6 | In stock | |
| 50 mg | $428.8 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
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The active product of AZD1152, a potent, selective inhibitor of Aurora B kinase with IC50 of 0.37 nM; displays >3,700-fol selectivity for Aurora B over Aurora A; potently inhibits the growth of human colon, lung, and hematologic tumor xenografts.
| M.Wt | 507.5599 | |
| Formula | C26H30FN7O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)- |
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1. Grundy M, et al. Mol Cancer Ther. 2010 Mar;9(3):661-72.
2. Mortlock AA, et al. J Med Chem. 2007 May 3;50(9):2213-24. Epub 2007 Mar 21.
3. Wilkinson RW, et al. Clin Cancer Res. 2007 Jun 15;13(12):3682-8.
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