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Chemical Structure : AZD1283
CAS No.: 919351-41-0
Catalog No.: PC-20648Not For Human Use, Lab Use Only.
AZD1283 (AZD-1283) is a potent, selective P2Y12 receptor antagonist with binding IC50 of 11 nM, and IC50 of 3.2 uM in washed platelet assay (WPA).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $138 | In stock | |
| 10 mg | $218 | In stock | |
| 25 mg | $378 | In stock | |
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| 100 mg | Get quote |
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AZD1283 (AZD-1283) is a potent, selective P2Y12 receptor antagonist with binding IC50 of 11 nM, and IC50 of 3.2 uM in washed platelet assay (WPA).
AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED50 values of 3.0 μg/kg/min.
| M.Wt | 470.54 | |
| Formula | C23H26N4O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
ethyl 6-(4-((benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate |
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1. Kong D, et al. J Med Chem. 2019 Mar 28;62(6):3088-3106.
2. Bach P, et al. J Med Chem. 2013 Sep 12;56(17):7015-24.
3. Zhang K, et al. Nature. 2014 May 1;509(7498):115-8.
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