| Cat. No. |
Product Name |
Information |
| PC-23840 |
Prasugrel
P2Y12 antagonist
|
Prasugrel (CS-747, LY640315) is an orally active and potent P2Y12 receptor antagonist, inhibits ADP-induced platelet aggregation, also is a candidate USP1 inhibitor. |
| PC-23316 |
PSB-24040
GPR17 antagonist
|
PSB-24040 is a potent antagonist of orphan receptor GPR17 with Ki of 83.2 nM, and pIC50 of 7.48 in calcium mobilization assays. |
| PC-23315 |
PSB-22269
GPR17 antagonist
|
PSB-22269 is a potent antagonist of orphan receptor GPR17 with Ki of 8.91 nM, and pIC50 of 6.9 in calcium mobilization assays. |
| PC-22103 |
PPTN hydrochloride
P2Y14 antagonist
|
PPTN hydrochloride is a potent, highly specific antagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays. |
| PC-22102 |
PPTN
P2Y14 antagonist
|
PPTN is a potent, highly specific antagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays. |
| PC-20993 |
AR-C118925XX
P2Y2 antagonist
|
AR-C118925XX is a potent, selective, competitive P2Y2 receptor antagonist with pA2 values of 37.2 nM and 51.3 nM in calcium and β-arrestin assays, respectively. |
| PC-20648 |
AZD1283
P2Y12 antagonist
|
AZD1283 (AZD-1283) is a potent, selective P2Y12 receptor antagonist with binding IC50 of 11 nM, and IC50 of 3.2 uM in washed platelet assay (WPA). |
| PC-49620 |
MRS4853
P2Y6 inhibitor
|
MRS4853 is a selective P2Y6 receptor (P2Y6R) antagonist with IC50 of 0.46 uM (hP2Y6R), displays weak affinity for mP2Y6R (IC50=6.15 uM). |
| PC-35578 |
ACT-281959
P2Y12 inhibitor
|
ACT-281959 (ACT281959) is the prodrug of ACT-246475, which is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
| PC-35577 |
ACT-246475
P2Y12 antagonist
|
Selatogrel (ACT-246475) is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
| PC-35051 |
PPTN trifluoroacetate salt
P2Y14 antagonist
|
PPTN is a potent, highly specific antagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays. |
| PC-35049 |
MRS4478
P2Y14 antagonist
|
MRS4478 is a potent, highly specific antagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors. |
