PSB-22269 | GPR17 antagonist | Probechem Biochemicals

Chemical Structure : PSB-22269

Catalog No.: PC-23315Not For Human Use, Lab Use Only.

PSB-22269 is a potent antagonist of orphan receptor GPR17 with Ki of 8.91 nM, and pIC50 of 6.9 in calcium mobilization assays.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PSB-22269 is a potent antagonist of orphan receptor GPR17 with Ki of 8.91 nM, and pIC50 of 6.9 in calcium mobilization assays.

M.Wt	443.46
Formula	C26H21NO6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-Methoxy-2-(5-(3′-methoxy-[1,1′-biphenyl]-2-yl)furan-2-carboxamido)benzoic Acid

1. Boshta NM, et al. J Med Chem. 2024 Nov 1. doi: 10.1021/acs.jmedchem.4c01755.