| Cat. No. |
Product Name |
Information |
| PC-21206 |
PSB-0739
P2Y12 antagonist
|
PSB-0739 is a high potent, non-nucleotide-derived competitive antagonist of platelet P2Y12 receptor with Ki of 24.9 nM. |
| PC-20994 |
MRS2768 tetrasodium salt
P2Y2R agonist
|
MRS2768 is a selective P2Y2 receptor agonist with EC50 of 1.89 uM, shows no effect for human P2Y4 or P2Y6 receptors. |
| PC-20993 |
AR-C118925
P2Y2R antagonist
|
AR-C118925 is a potent, selective, competitive P2Y2 receptor antagonist with pA2 values of 37.2 nM and 51.3 nM in calcium and β-arrestin assays, respectively. |
| PC-20962 |
MRS4833
P2Y14 inhibitor
|
MRS4833 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 5.9 nM, Ki of 3.44 nM (human P2Y14R). |
| PC-20961 |
MRS4654
P2Y14 inhibitor
|
MRS4654 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 15 nM and 18.6 nM for human and rat P2Y14R, respectively. |
| PC-20960 |
MRS4738
P2Y14 inhibitor
|
MRS4738 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 3.11 nM. |
| PC-20959 |
MRS4608
P2Y14 inhibitor
|
MRS4608 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 6.32 nM. |
| PC-20648 |
AZD1283
P2Y12 antagonist
|
AZD1283 (AZD-1283) is a potent, selective P2Y12 receptor antagonist with binding IC50 of 11 nM, and IC50 of 3.2 uM in washed platelet assay (WPA). |
| PC-49620 |
MRS4853
P2Y6 inhibitor
|
MRS4853 is a selective P2Y6 receptor (P2Y6R) antagonist with IC50 of 0.46 uM (hP2Y6R), displays weak affinity for mP2Y6R (IC50=6.15 uM). |
| PC-35578 |
ACT-281959
|
ACT-281959 (ACT281959) is the prodrug of ACT-246475, which is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
| PC-35049 |
MRS4478
|
MRS4478 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors.. |
| PC-35048 |
MRS4458
|
MRS4458 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 169 nM, does not display extensive off-target interactions with biogenic amine receptors.. |
