Chemical Structure : Elinogrel
CAS No.: 936500-94-6
Catalog No.: PC-61587Not For Human Use, Lab Use Only.
Elinogrel (PRT060128) is a selective, reversible, competitive and direct-acting P2Y12 receptor antagonist with IC50 of 20 nM.
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Elinogrel (PRT060128) is a selective, reversible, competitive and direct-acting P2Y12 receptor antagonist with IC50 of 20 nM.
Elinogrel (PRT060128) shows potent antiplatelet effects for the treatment of acute coronary syndrome and prevention of secondary thrombotic events.
M.Wt | 523.945 | |
Formula | C20H15ClFN5O5S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-[4-(6-Fluoro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)phenyl]-N'-[(5-chlorothiophen-2-yl)sulfonyl]urea |
1. Siller-Matula JM, et al. Br J Pharmacol. 2010 Feb 1;159(3):502-17.
2. Leonardi S, et al. Am Heart J. 2010 Jul;160(1):65-72.
3. Oestreich JH. Curr Opin Investig Drugs. 2010 Mar;11(3):340-8.
4. André P, et al. J Pharmacol Exp Ther. 2011 Jul;338(1):22-30.
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