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Chemical Structure : Cangrelor tetrasodium
CAS No.: 163706-36-3
Catalog No.: PC-61585Not For Human Use, Lab Use Only.
Cangrelor tetrasodium (AR-C69931MX) is a potent, selective P2T/P2Y12 receptor antagonist with IC50 of 0.4 nM against ADP-induced aggregation of human platelets.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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Cangrelor tetrasodium (AR-C69931MX) is a potent, selective P2T/P2Y12 receptor antagonist with IC50 of 0.4 nM against ADP-induced aggregation of human platelets.
Cangrelor displays >1,000-fold selectivity over other P2 receptor family.
Cangrelor antagonizes the ex vivo and in vivo aggregatory actions of ADP, and displays a rapid onset and offset of action with the ability to prevent occlusive arterial thrombus formation.
| M.Wt | 864.29 | |
| Formula | C17H21Cl2F3N5Na4O12P3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5'-Adenylic acid, N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-, monoanhydride with (dichloromethylene)bis[phosphonic acid] (9CI) |
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1. Ingall AH, et al. J Med Chem. 1999 Jan 28;42(2):213-20.
2. Huang J, et al. J Pharmacol Exp Ther. 2000 Nov;295(2):492-9.
3. Storey RF, et al. Br J Haematol. 2000 Sep;110(4):925-34.
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