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MRS4853

Chemical Structure : MRS4853

CAS No.: 2839477-13-1

MRS4853

Catalog No.: PC-49620Not For Human Use, Lab Use Only.

MRS4853 is a selective P2Y6 receptor (P2Y6R) antagonist with IC50 of 0.46 uM (hP2Y6R), displays weak affinity for mP2Y6R (IC50=6.15 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MRS4853 is a selective P2Y6 receptor (P2Y6R) antagonist with IC50 of 0.46 uM (hP2Y6R), displays weak affinity for mP2Y6R (IC50=6.15 uM).

    Physicochemical Properties

    M.Wt 383.44
    Formula C18H20F3NO3Si
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    triethyl((3-nitro-2-(trifluoromethyl)-2H-chromen-8-yl)ethynyl)silane

    References

    1. Jung YH, et al. Bioorg Med Chem Lett. 2022 Nov 1;75:128981.

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