Chemical Structure : PPTN hydrochloride
CAS No.:
1992047-65-0
PPTN hydrochloride
Catalog No. : PC-22103Not For Human Use, Lab Use Only.
PPTN hydrochloride is a potent, highly specific antagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2210301
Biological Activity
PPTN hydrochloride is a potent, highly specific antagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays.
Physicochemical Properties
M.Wt
511.97
Formula
C29H25ClF3NO2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-Naphthalenecarboxylic acid, 4-[4-(4-piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-, hydrochloride (1:1)
References
1. Yu J, et al. J Med Chem. 2018 May 16. doi: 10.1021/acs.jmedchem.8b00168.
2. Junker A, et al. J Med Chem. 2016 Jul 14;59(13):6149-68.
3. Barrett MO, et al. Mol Pharmacol. 2013 Jul;84(1):41-9.
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