AZD3470 | PRMT5 inhibitor | Probechem Biochemicals

Chemical Structure : AZD3470

Catalog No.: PC-26788Not For Human Use, Lab Use Only.

AZD3470 (AZD-3470) is a potent, seleective MTA-cooperative PRMT5 inhibitor, targets MTAP deficient advanced/metastatic cancer cells.

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Biological Activity

AZD3470 (AZD-3470) is a potent, seleective MTA-cooperative PRMT5 inhibitor, targets MTAP deficient advanced/metastatic cancer cells.

M.Wt	435.43
Formula	C23H19F2N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-((5-amino-6-fluoro-1H-pyrrolo[3,2-b]pyridin-2-yl)methyl)-1'-(but-2-yn-1-yl)-5-fluorospiro[isoindoline-1,3'-pyrrolidine]-2',3-dione

1. Jelena Urosevic, et al. Cancer Res (2026) 86 (7_Supplement): 4489.