Chemical Structure : AZD6280
CAS No.: 942436-93-3
Catalog No.: PC-62765Not For Human Use, Lab Use Only.
AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7.
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|---|---|---|---|
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| 5 mg | $478 | In stock | |
| 10 mg | $758 | In stock | |
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AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7.
AZD6280 exerts neutral antagonism at the α1-subunit and partial efficacy at the α2,3-subunits over the α5-subunit.
AZD6280 shows potential for the treatment of anxiety disorders.
| M.Wt | 366.421 | |
| Formula | C20H22N4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-amino-8-(2,5-dimethoxyphenyl)-N-propyl-3-cinnolinecarboxamide |
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1. Jucaite A, et al. Psychopharmacology (Berl). 2017 Feb;234(4):707-716.
2. Chen X, et al. J Clin Psychopharmacol. 2015 Feb;35(1):22-33.
3. Te Beek ET, et al. Clin Pharmacol Drug Dev. 2015 Mar;4(2):149-54.

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