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AZD6605

Chemical Structure : AZD6605

CAS No.: 893556-15-5

AZD6605 (AZD-6605)

Catalog No.: PC-28296Not For Human Use, Lab Use Only.

AZD6605 (AZD-6605) is a potent and selective inhibitor of MMP-13 (MMP13) with IC50 of 4.7 nM, 430-fold selective over MMP-14.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AZD6605 (AZD-6605) is a potent and selective inhibitor of MMP-13 (MMP13) with IC50 of 4.7 nM, 430-fold selective over MMP-14.

Physicochemical Properties

M.Wt 483.44
Formula C18H21F4N3O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,4-Imidazolidinedione, 5-methyl-5-[[[4-[4-(1,1,2,2-tetrafluoroethoxy)phenoxy]-1-piperidinyl]sulfonyl]methyl]-, (5S)-

References

1. De Savi C, et al. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4705-12.

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