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Ac-Glu-Glu-Arg-kbt

Chemical Structure : Ac-Glu-Glu-Arg-kbt

CAS No.:

Ac-Glu-Glu-Arg-kbt (PM-3)

Catalog No.: PC-24590Not For Human Use, Lab Use Only.

PM-3 (Ac-Glu-Glu-Arg-kbt) is a potent dual TMPRSS11D and TMPRSS2 inhibitor with IC50 of 7.1 nM and 3.2 nM respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PM-3 (Ac-Glu-Glu-Arg-kbt) is a potent dual TMPRSS11D and TMPRSS2 inhibitor with IC50 of 7.1 nM and 3.2 nM respectively.

Physicochemical Properties

M.Wt 591.64
Formula C25H33N7O8S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-4-acetamido-5-(((S)-1-(((S)-1-(benzo[d]thiazol-2-yl)-5-guanidino-1-oxopentan-2-yl)amino)-4-carboxy-1-oxobutan-2-yl)amino)-5-oxopentanoic acid

References

1. Fraser BJ, et al. Nat Commun. 2025 May 10;16(1):4351.

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