AcTor

Chemical Structure : AcTor

Catalog No.: PC-26698Not For Human Use, Lab Use Only.

AcTor is a specific small molecule TSC2 inhibitor and mTOR stimulator, activates mTORC1 in the presence of ixazomib and potentiates ixazomibactivity across multiple AML cell lines.

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Biological Activity

AcTor is a specific small molecule TSC2 inhibitor and mTOR stimulator, activates mTORC1 in the presence of ixazomib and potentiates ixazomibactivity across multiple AML cell lines.

Physicochemical Properties

M.Wt	907.16
Formula	C48H58N8O6S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	thiazol-5-ylmethyl ((2S,4R,5S)-6-(4-(1H-indol-3-yl)phenyl)-4-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-4-morpholinobutanamido)-1-phenylhexan-2-yl)carbamate

References

1. Pattanayak SP, et al. Res Sq [Preprint]. 2026 Apr 23:rs.3.rs-9405584.

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AcTor

Biological Activity

Physicochemical Properties

References

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