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Chemical Structure : Agomelatine hydrochloride
CAS No.: 1176316-99-6
Catalog No.: PC-45161Not For Human Use, Lab Use Only.
Agomelatine hydrochloride (S-20098) melatonin receptor agonist of MT1 (Ki=0.1nM) and MT2 (Ki=0.12nM), and a 5-HT2C (Ki=631nM) receptor antagonist.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $118 | In stock | |
| 50 mg | $188 | In stock | |
| 100 mg | $328 | In stock | |
| 250 mg | Get quote |
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Agomelatine hydrochloride (S-20098) melatonin receptor agonist of MT1 (Ki=0.1nM) and MT2 (Ki=0.12nM), and a 5-HT2C (Ki=631nM) receptor antagonist.
Agomelatine has no effect on monoamine uptake and no affinity for adrenergic, histaminergic, cholinergic, dopaminergic and benzodiazepine receptors, nor other serotonergic receptors.
Agomelatine is a melatonergic antidepressant treatment of major depressive disorder with relatively favorable side effect profile.
| M.Wt | 279.7619 | |
| Formula | C15H18ClNO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]- (hydrochloride)(1:1) |
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1. Depreux P, et al. J Med Chem. 1994 Sep 30;37(20):3231-9.
2. Wiley JL, et al. Psychopharmacology (Berl). 1998 Dec;140(4):503-9.
3. Ying SW, et al. Eur J Pharmacol. 1996 Jan 18;296(1):33-42.
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