Aleglitazar | PPARα/γ agonist | Probechem Biochemicals

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Chemical Structure : Aleglitazar

Aleglitazar (R1439;RO0728804;R-1439;RO-0728804;R 1439;RO 0728804)

Catalog No.: PC-44041Not For Human Use, Lab Use Only.

Aleglitazar (R1439, RO 0728804) is a potent and balanced dual PPARα/γ agonist (EC50= 50/21 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Aleglitazar (R1439, RO 0728804) is a potent and balanced dual PPARα/γ agonist (EC50= 50/21 nM).
Aleglitazar (R1439, RO 0728804) shows high efficacy in animal models of type II diabetes.

Physicochemical Properties

M.Wt	437.5081
Formula	C24H23NO5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αS)-

References

1. Bénardeau A, et al. Bioorg Med Chem Lett. 2009 May 1;19(9):2468-73.

2. Qian J, et al. Cardiovasc Drugs Ther. 2016 Apr;30(2):129-41.

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Aleglitazar (R1439;RO0728804;R-1439;RO-0728804;R 1439;RO 0728804)

Biological Activity

Physicochemical Properties

References

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