| Cat. No. |
Product Name |
Information |
| PC-28625 |
PBM-342
PPAR-β/δ modulator
|
PBM-342 is a novel PPARβ/δ modulator, promotes myotube viability, upregulates PPAR-β/δ and PDK4 expression, enhances myoblast fusion, and shifts fiber-type composition toward an oxidative phenotype. |
| PC-28015 |
6-Shogaol
PPARγ activator
|
6-Shogaol ([6]-Shogaol) is an active compound isolated from ginger root (Rhizoma Zingiberis Recens) with various biological activities including anticancer, anti-inflammation, and anti-oxidation, inhibits breast and colon cancer cell proliferation through activation of PPARγ. |
| PC-27669 |
MHY5535
PPARα antagonist
|
MHY5535 is a potent PPARα antagonist, inhibits PPARα transcriptional activity with IC50 of 0.54 uM, effectively reduces ovarian cancer stem cells (CSCs) viability and self-renewal. |
| PC-26999 |
DN203316
PPARδ agonist
|
DN203316 is a potent, selective peroxisome proliferator-activated receptor delta (PPARδ) agonist with EC50 of 0.02 uM (hPPARδ). |
| PC-24240 |
Glabridin
PPARγ agonist
|
Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ with EC50 of 6.1 uM, inhibits NADPH oxidase-induced cell-mediated oxidation, exhibits antioxidant, anti-bacterial, antitumor and anti-inflammatory activities. |
| PC-24111 |
TPST-1120
PPARα inhibitor
|
Amezalpat (TPST-1120, TPST1120) is potent, selective and orally bioavailable inhibitor of peroxisome proliferator-activated receptor α (PPARα) with IC50 of 0.04 uM (human PPARα), >250-fold selectivity over the other PPAR isoforms (PPAR β/δ and γ). |
| PC-22387 |
GW0742
PPARδ agonist
|
GW0742 is a potent, selective small molecule agonist of PPARδ with EC50 of 1.0 nM, 1000-fold selectivity over the other human PPAR subtypes. |
| PC-22386 |
LDT409
PPAR agonist
|
LDT409 is a small molecule, orally active partial agonist of pan PPARα/γ/δ with EC50 of 0.5 uM, 0.9 uM and 33 uM for huamn PPARα and PPARγ, respectively. |
| PC-20679 |
FTX-6746
PPARγ inhibitor
|
FTX-6746 (FTX6746) is a potent, highly selective and orally active proliferator-activated receptor gamma (PPARG, PPARγ) inhibitor with cellular IC50 of 5 nM, >100-fold selectivity over PPARD and PPARA. |
| PC-20667 |
FX-909
PPARγ inverse agonist
|
FX-909 (FX909) is a potent, selective and covalent peroxisome proliferator-activated receptor gamma (PPARG, PPARγ) inverse agonist with cellular IC50 of 1 nM, >2000-fold selective over PPARα/PPARδ. |
| PC-20276 |
GSK3787
PPARδ antagonist
|
GSK3787 (GSK 3787) is a potent, selective and irreversible antagonist of PPARdelta (PPARδ) with binding pIC50 of 6.6, without measurable affinity for hPPARα or hPPARγ. |
| PC-49401 |
SR10221
PPARγ inverse agonist
|
SR10221 is a potent, selective PPARγ inverse agonist with IC50 of 13 nM in biochemical peptide recruitment assays, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines. |
