| Cat. No. |
Product Name |
Information |
| PC-35669 |
DS-6930b
PPARγ agonist
|
DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%. |
| PC-35555 |
Fonadelpar
PPARδ agonist
|
Fonadelpar (NPS-005, SJP-0035) is a potent, selective peroxisome proliferator activated receptor δ (PPARδ) agonist for the treatment of corneal disorders. |
| PC-35153 |
PPARα activator compound 3
PPARα agonist
|
PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo. |
| PC-43387 |
T0070907
PPARγ inhibitor
|
T0070907 is a potent, selective, covalent PPARγ antagonist with binding IC50 of 1 nM, >800-fold preference for PPARγ over PPARα and PPARδ. |
| PC-43009 |
GSK0660
PPARβ/δ inhibitor
|
GSK0660 is a potent, selective, dual PPARβ/δ antagonist with pIC50 of 6.8 (160 nM), shows no activity on PPARα and PPARγ (IC50>10 uM). |
| PC-63148 |
AZD6610
PPARα/γ agonist
|
AZD6610 is a potent, dual peroxisome proliferator-activated receptor (PPAR) α/γ agonist for treatment of diabetes mellitus. |
| PC-62872 |
GW6471
PPARα inhibitor
|
GW6471 is a potent PPARα antagonist with IC50 of 0.24 uM, enhances the binding affinity of the PPARα ligand-binding domain to the co-repressor proteins SMRT and NCoR. |
| PC-62445 |
GW7647
PPARα agonist, USP1 inhibitor
|
GW-7647 is a potent, selective PPARα agonist with EC50 of 6 nM, dispalys high selectivity over PPARγ and PPARδ. |
| PC-62431 |
MCC-555
PPARγ agonist
|
MCC-555 (Isaglitazone, Netoglitazone, RWJ 241947) is an activating ligand of PPARγ with EC50 of 8 uM, exhibts greater antidiabetic potency that other TZDs including BRL49653. |
| PC-62345 |
MRL20
PPARγ agonist
|
MRL20 is a novel synthetic PPARγ ligand and orthosteric agonist with canonical LBP binding affinity of 2 nM. |
| PC-62344 |
SR16832
PPARγ inhibitor
|
SR16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone. |
| PC-61631 |
ABTL0812
PPAR agonist
|
ABTL0812 (2-hydroxylinoleic acid) is a novel first-in-class, small molecule that inhibits the Akt/mTORC1 axis and shows antiproliferative effect on tumor cells, binds to PPARα and PPARγ (Ki=7.1 and 4.7 uM, respectively). |
