Chemical Structure : DS-6930b
Catalog No.: PC-35669Not For Human Use, Lab Use Only.
DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%.
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DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%.
DS-6930b significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays.
DS-6930b demonstrates high PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity.
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Appearance | Solid | |
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10 mM in DMSO |
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