DS-6930b | Probechem Biochemicals

Chemical Structure : DS-6930b

DS-6930b (DS-6930 calcium salt;DS6930b)

Catalog No.: PC-35669Not For Human Use, Lab Use Only.

DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%.

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Biological Activity

DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%.
DS-6930b significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays.
DS-6930b demonstrates high PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity.

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

References

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DS-6930b (DS-6930 calcium salt;DS6930b)

Biological Activity

Physicochemical Properties

References

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