| Cat. No. |
Product Name |
Information |
| PC-24240 |
Glabridin
PPARγ agonist
|
Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ with EC50 of 6.1 uM, inhibits NADPH oxidase-induced cell-mediated oxidation, exhibits antioxidant, anti-bacterial, antitumor and anti-inflammatory activities. |
| PC-24111 |
TPST-1120
PPARα inhibitor
|
Amezalpat (TPST-1120, TPST1120) is potent, selective and orally bioavailable inhibitor of peroxisome proliferator-activated receptor α (PPARα) with IC50 of 0.04 uM (human PPARα), >250-fold selectivity over the other PPAR isoforms (PPAR β/δ and γ). |
| PC-24032 |
PPARα agonist A190
PPARδ agonist
|
PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms. |
| PC-23875 |
TIPP-401
PPARα/δ agonist
|
TIPP-401 is a potent, selective PPARα/δ agonist with EC50 of 10/12 nM, >150-fold selective PPARγ. |
| PC-23874 |
TIPP-204
PPARδ agonist
|
TIPP-204 is a potent, selective PPARδ agonist with EC50 of 0.91 nM, >250-fold selective PPARα and PPARγ. |
| PC-23873 |
TIPP-703
PPAR pan agonist
|
TIPP-703 is a potent, PPARα/δ/γ pan agonist with EC50 of 61/120/43 nM respectively. |
| PC-23809 |
Fenofibric acid
PPAR agonist
|
Fenofibric acid, an active metabolite of fenofibrate and anti-inflammatory agent, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively, also inhibits COX-2 with IC50 of 48 nM. |
| PC-23279 |
Farglitazar
PPARγ agonist
|
Farglitazar (GI262570) is a potent, selective PPARgamma (PPARγ) agonist. |
| PC-22731 |
PPARα agonist A229
PPARα agonist
|
A229 is a potent, selective peroxisome proliferator-activated receptor alpha (PPARα) agonist with EC50 of 590 nM, shows subtype selectivity for PPARα in luciferase-based cell assay. |
| PC-22387 |
GW0742
PPARδ agonist
|
GW0742 is a potent, selective small molecule agonist of PPARδ with EC50 of 1.0 nM, 1000-fold selectivity over the other human PPAR subtypes. |
| PC-22386 |
LDT409
PPAR agonist
|
LDT409 is a small molecule, orally active partial agonist of pan PPARα/γ/δ with EC50 of 0.5 uM, 0.9 uM and 33 uM for huamn PPARα and PPARγ, respectively. |
| PC-22207 |
E09241
Osteoprotegerin upregulator, PPARδ activator
|
E09241 is a small molecule osteoprotegerin (OPG) upregulator with EC50 of 1.23 uM, effectively promotes osteogenesis and inhibits osteoclastogenesis through activating the PPARδ signaling pathway. |
