| Cat. No. |
Product Name |
Information |
| PC-45067 |
Elafibranor
PPARα/δ agonist
|
Elafibranor (GFT505) is a potent dual PPAR α/δ agonist with EC50 of 45 and 175 nM, respectively. |
| PC-45390 |
Pemafibrate
PPARα agonist
|
Pemafibrate (K-877) is a highly potent, specific PPARα agonist with EC50 of 1 nM. |
| PC-27414 |
Busegampar
PPARγ agonist
|
Busegampar is a potent, selective peroxisome proliferator activated receptor gamma (PPARγ) agonist. |
| PC-26903 |
DTMB
PPAR agonist
|
DTMB is a synthetic tryptophan derivative and PPAR α/δ/γ agonist, binds to PPAR α/δ/γ LBD, ameliorates the chronic inflammation and Aβ pathological progression of Alzheimer’s disease. |
| PC-26571 |
10-oxostearic acid
PPARα agonist
|
10-oxostearic acid (10-oxoSA) is a microbial metabolite derived from oleic acid as a potent and selective agonist of the lipid-sensing nuclear receptor peroxisome proliferator-activated receptor alpha (PPARα), binds to hPPARα-LBD with EC50 of 78.2 nM. |
| PC-26222 |
Pioglitazone
PPARγ agonist
|
Pioglitazone (U 72107) is an orally active and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively, highly selective over PPARα and PPARδ |
| PC-25042 |
Deutaleglitazar
PPARα/γ agonist
|
Deutaleglitazar is the deuterated form of Aleglitazar (R1439, RO 0728804), a potent and balanced dual PPARα/γ agonist (EC50= 50/21 nM). |
| PC-25016 |
SR33068
PPARγ inverse agonist
|
SR33068 is a potent, selective and covalent inverse PPARγ agonist. |
| PC-25015 |
GW9662
PPARγ antagonist
|
GW9662 is a potent and selective PPARγ antagonist with IC50 of 3.3 nM, shows 10 and 1000-fold selectivity over PPARα and PPARδ, respectively. |
| PC-24032 |
PPARα agonist A190
PPARδ agonist
|
PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms. |
| PC-23875 |
TIPP-401
PPARα/δ agonist
|
TIPP-401 is a potent, selective PPARα/δ agonist with EC50 of 10/12 nM, >150-fold selective PPARγ. |
| PC-23874 |
TIPP-204
PPARδ agonist
|
TIPP-204 is a potent, selective PPARδ agonist with EC50 of 0.91 nM, >250-fold selective PPARα and PPARγ. |
