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Cat. No. Product Name Information
PC-24240

Glabridin

PPARγ agonist

Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ with EC50 of 6.1 uM, inhibits NADPH oxidase-induced cell-mediated oxidation, exhibits antioxidant, anti-bacterial, antitumor and anti-inflammatory activities.
PC-24111

TPST-1120

PPARα inhibitor

Amezalpat (TPST-1120, TPST1120) is potent, selective and orally bioavailable inhibitor of peroxisome proliferator-activated receptor α (PPARα) with IC50 of 0.04 uM (human PPARα), >250-fold selectivity over the other PPAR isoforms (PPAR β/δ and γ).
PC-24032

PPARα agonist A190

PPARδ agonist

PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms.
PC-23875

TIPP-401

PPARα/δ agonist

TIPP-401 is a potent, selective PPARα/δ agonist with EC50 of 10/12 nM, >150-fold selective PPARγ.
PC-23874

TIPP-204

PPARδ agonist

TIPP-204 is a potent, selective PPARδ agonist with EC50 of 0.91 nM, >250-fold selective PPARα and PPARγ.
PC-23873

TIPP-703

PPAR pan agonist

TIPP-703 is a potent, PPARα/δ/γ pan agonist with EC50 of 61/120/43 nM respectively.
PC-23809

Fenofibric acid

PPAR agonist

Fenofibric acid, an active metabolite of fenofibrate and anti-inflammatory agent, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively, also inhibits COX-2 with IC50 of 48 nM.
PC-23279

Farglitazar

PPARγ agonist

Farglitazar (GI262570) is a potent, selective PPARgamma (PPARγ) agonist.
PC-22731

PPARα agonist A229

PPARα agonist

A229 is a potent, selective peroxisome proliferator-activated receptor alpha (PPARα) agonist with EC50 of 590 nM, shows subtype selectivity for PPARα in luciferase-based cell assay.
PC-22387

GW0742

PPARδ agonist

GW0742 is a potent, selective small molecule agonist of PPARδ with EC50 of 1.0 nM, 1000-fold selectivity over the other human PPAR subtypes.
PC-22386

LDT409

PPAR agonist

LDT409 is a small molecule, orally active partial agonist of pan PPARα/γ/δ with EC50 of 0.5 uM, 0.9 uM and 33 uM for huamn PPARα and PPARγ, respectively.
PC-22207

E09241

Osteoprotegerin upregulator, PPARδ activator

E09241 is a small molecule osteoprotegerin (OPG) upregulator with EC50 of 1.23 uM, effectively promotes osteogenesis and inhibits osteoclastogenesis through activating the PPARδ signaling pathway.

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