| Cat. No. |
Product Name |
Information |
| PC-23809 |
Fenofibric acid
PPAR agonist
|
Fenofibric acid, an active metabolite of fenofibrate and anti-inflammatory agent, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively, also inhibits COX-2 with IC50 of 48 nM. |
| PC-23279 |
Farglitazar
PPARγ agonist
|
Farglitazar (GI262570) is a potent, selective PPARgamma (PPARγ) agonist. |
| PC-22731 |
PPARα agonist A229
PPARα agonist
|
A229 is a potent, selective peroxisome proliferator-activated receptor alpha (PPARα) agonist with EC50 of 590 nM, shows subtype selectivity for PPARα in luciferase-based cell assay. |
| PC-22387 |
GW0742
PPARδ agonist
|
GW0742 is a potent, selective small molecule agonist of PPARδ with EC50 of 1.0 nM, 1000-fold selectivity over the other human PPAR subtypes. |
| PC-22386 |
LDT409
PPAR agonist
|
LDT409 is a small molecule, orally active partial agonist of pan PPARα/γ/δ with EC50 of 0.5 uM, 0.9 uM and 33 uM for huamn PPARα and PPARγ, respectively. |
| PC-22207 |
E09241
Osteoprotegerin upregulator, PPARδ activator
|
E09241 is a small molecule osteoprotegerin (OPG) upregulator with EC50 of 1.23 uM, effectively promotes osteogenesis and inhibits osteoclastogenesis through activating the PPARδ signaling pathway. |
| PC-22205 |
E0924G
Osteoprotegerin upregulator, PPARδ activator
|
E0924G is a small molecule osteoprotegerin (OPG, EC50=0.29 uM) and runt-related transcription factor 2 (RUNX2) upregulator, effectively promotes osteogenesis and inhibits osteoclastogenesis through activating the PPARδ signaling pathway. |
| PC-44047 |
Choline Fenofibrate
|
A PPARα agonist used for treatment of hyperlipidemia. |
| PC-45753 |
Saroglitazar magnesium salt
|
A novel PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively. |
