| Cat. No. |
Product Name |
Information |
| PC-73409 |
Bocidelpar
PPARδ agonist
|
Bocidelpar (ASP-0367, MA-0211, MTB-1) is a potent selective peroxisome proliferator-activated receptor delta (PPARδ) agonist with potential against mitochondrial myopathies. |
| PC-73019 |
MSDC0160
MPC inhibitor
|
MSDC0160 (Mitoglitazone, MSDC-0160) is a small molecule targeting mitochondrial pyruvate carrier (MPC), also is an insulin sensitizer with anti-diabetes activities. |
| PC-72950 |
PPARγ pSer273-IN-10
PPARγ pSer273 inhibitor
|
PPARγ pSer273-IN-10 is a specific, in vivo-active small molecule inhibitor of CDK5-mediated Ser273 phosphorylation of PPARγ without classical PPARγ agonism. |
| PC-72656 |
NXT629
PPARα antagonist
|
NXT629 (NXT-629) is a potent, selective PPARα antagonist with IC50 of 78 nM, no effect against PPARδ and PPARγ (IC50>30 uM). |
| PC-72023 |
FK614
PPARγ agonist
|
FK614 (FK 614) is a non-thiazolidinedione (TZD), orally active PPARγ agonist. |
| PC-38250 |
WO95E
PPARγ agonist
|
WO95E is a novel potent, synthetic ligand (partial agonist) of PPARγ, directly binds to PPARγ with IC50 of 11 nM. |
| PC-38051 |
EHP-101
PPARγ/CB2 agonist
|
EHP-101 (Etrinabdione, VCE-004.8) is an orally active, specific PPARγ and CB2 receptor dual agonist. |
| PC-35942 |
BR101549
PPARγ agonist
|
BR101549 (BR-101549) is a novel PPARγ non-TZD agonist with EC50 of 1.73 uM (Amax 120%).. |
| PC-35795 |
Chiglitazar
PPARα/γ agonist
|
Chiglitazar (Carfloglitazar, CS-038, CS038) is a potent, dual PPARα/γ dual agonist with EC50 of 1.2, 0.08, 1.7 uM for PPARα, PPARγ and PPARδ, respectively. |
| PC-35702 |
MA-0204
PPARδ modulator
|
MA-0204 (MA0204) is a potent, selective PPARδ modulator with EC50 of 0.4 nM (human PPARδ), dispalys no activity (10,000-fold selectivity) against PPARα and PPARγ. |
| PC-35674 |
DS-6930
PPARγ agonist
|
DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%. |
| PC-35669 |
DS-6930b
PPARγ agonist
|
DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%. |
