Chemical Structure : Eupatilin
CAS No.: 22368-21-4
Catalog No.: PC-36079Not For Human Use, Lab Use Only.
Eupatilin (NSC 122413, Stillen) is a pharmacologically active flavone derived from Artemisia plants, possess anti-inflammatory, anti-oxidative and anti-cancer activities.
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|---|---|---|---|
| 10 mg | $58 | In stock | |
| 25 mg | $88 | In stock | |
| 50 mg | $128 | In stock | |
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Eupatilin (NSC 122413, Stillen) is a pharmacologically active flavone derived from Artemisia plants, possess anti-inflammatory, anti-oxidative and anti-cancer activities, is a PPARα agonist.
Eupatilin induces cell cycle arrest in ras-transformed human mammary epithelial cells.
Eupatilin attenuates aortic smooth muscle cell proliferation and migration by inhibiting PI3K, MKK3/6, and MKK4 activities.
Eupatilin inhibits angiogenesis-mediated human hepatocellular metastasis by reducing MMP-2 and VEGF signaling.
| M.Wt | 344.32 | |
| Formula | C18H16O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one |
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1. Kim DH, et al. Biochem Pharmacol. 2004 Sep 15;68(6):1081-7.
2. Koshihara Y, et al. FEBS Lett. 1983 Jul 11;158(1):41-4.
3. Son JE, et al. Planta Med. 2013 Aug;79(12):1009-16.
4. Park JY, et al. Bioorg Med Chem Lett. 2018 Oct 15;28(19):3150-3154.

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