| Cat. No. |
Product Name |
Information |
| PC-61599 |
T3D-959
PPARγ/δ agonist
|
T3D 959 (DB-959) is a potent, brain penetrant, orally active dual PPARδ/PPARγ agonist with EC50 of 19/297 nM, respectively. |
| PC-61592 |
IVA-337
PPAR agonist
|
IVA-337 (Lanifibranor, IVA337)) is a potent, pan PPAR agonist with EC50 of 0.92 uM, 0.53 uM and 0.18 uM for human PPARα, PPARδ and PPARγ respectively. |
| PC-61381 |
Lenabasum
PPARγ ligand
|
Lenabasum (Ajulemic acid, IP-751, Anabasum) is a synthetic nonpsychoactive cannabinoid acid with potent analgesic and anti-inflammatory activity in vivo, binds directly and selectively to PPARγ. |
| PC-61150 |
Seladelpar
PPARδ agonist
|
Seladelpar (MBX-8025, RWJ800025) is a potent, selective, orally bioavailable PPAR-delta (PPARδ) agonist with EC50 of 2 nM, displays >750-fold selective over PPAR-α. |
| PC-61068 |
BMS-711939
PPARα agonist
|
BMS-711939 (BMS711939) is a potent and selective human PPARα agonist with EC50 of 4 nM, >1,000-fold selectivity over human PPARγ (EC50=4.5 uM) and PPARδ (EC50 >100 uM) in PPAR-GAL4 transactivation assays. |
| PC-60334 |
UHC1
PPARγ ligand
|
UHC1 is a potent, non-agonist PPARγ ligand that blocks CDK5-mediated PPARγ phosphorylation, without the classical agonism. |
| PC-60333 |
SR1664
PPARγ ligand
|
SR1664 (SR-1664) is a potent, non-agonist PPARγ ligand that blocks the Cdk5-mediated phosphorylation in vitro (IC50=80 nM) and in vivo, without the classical agonism. |
| PC-45391 |
Pemafibrate racemate
PPARα agonist
|
Pemafibrate racemate is the racemate of Pemafibrate, which is a highly potent, specific PPARα agonist with EC50 of 1 nM. |
| PC-45697 |
DG-172 dihydrochloride
PPARβ/δ inhibitor
|
DG-172 is a novel PPARβ/δ-selective ligand showing high binding affinity (IC50= 27 nM) and potent inverse agonistic properties. |
| PC-45781 |
L-165041
PPARδ agonist
|
L-165041 (L165041) is a selective PPARδ agonist with Ki of 6 nM, >120 fold selectivity over PPARγ. |
| PC-45908 |
Troglitazone
PPARγ agonist
|
Troglitazone (CS-045) is a PPARγ activator that has antidiabetic, anti-tumor and anti-inflammatory activities. |
| PC-45176 |
Fenofibrate
PPARα agonist
|
Fenofibrate is a PPARα agonist that exhibits EC50 of 18 and 30 uM for murine and human PPARα, respectively, in a transactivation assay. |
