Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Nuclear Receptor/Transcription Factor-PPAR-Lenabasum
Lenabasum

Chemical Structure : Lenabasum

CAS No.: 137945-48-3

Lenabasum (Ajulemic acid, IP-751, Anabasum)

Catalog No.: PC-61381Not For Human Use, Lab Use Only.

Lenabasum (Ajulemic acid, IP-751, Anabasum) is a synthetic nonpsychoactive cannabinoid acid with potent analgesic and anti-inflammatory activity in vivo, binds directly and selectively to PPARγ.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Lenabasum (Ajulemic acid, IP-751, Anabasum) is a synthetic nonpsychoactive cannabinoid acid with potent analgesic and anti-inflammatory activity in vivo, binds directly and selectively to PPARγ.
    Lenabasum produces significant antitumor activity and effects its actions primarily via CB(2) receptors.
    Lenabasum inhibits interleukin-8 promoter activity in a PPARgamma-dependent manner; significantly suppresses CYP-induced urinary frequency in rats at 10 mg/kg.

    Physicochemical Properties

    M.Wt 400.559
    Formula C25H36O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydro-6H-dibenzo[b,d]pyran-9-carboxylic acid

    References

    1. Recht LD, et al. Biochem Pharmacol. 2001 Sep 15;62(6):755-63.

    2. Ambrosio AL, et al. J Biol Chem. 2007 Jun 22;282(25):18625-33.

    3. Johnson DR, et al. J Cell Biochem. 2007 Jan 1;100(1):184-90.

    4. Hiragata S, et al. Urology. 2007 Jul;70(1):202-8.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: