 
                Chemical Structure : Troglitazone
CAS No.: 97322-87-7
Catalog No.: PC-45908Not For Human Use, Lab Use Only.
Troglitazone (CS-045) is a PPARγ activator that has antidiabetic, anti-tumor and anti-inflammatory activities.
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	Troglitazone (CS-045) is a PPARγ activator that has antidiabetic, anti-tumor and anti-inflammatory activities.
	Troglitazone binds to PPARγ and selectively induces the early growth response-1 gene expression.
	Troglitazone inhibits biosynthesis of cholesterol in CHO cell (IC50=8 ug/ml).
	Troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux.
| M.Wt | 441.5399 | |
| Formula | C24H27NO5S | |
| Appearance | Solid | |
| Storage | 
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| Solubility | 10 mM in DMSO | |
| Chemical Name/SMILES | 2,4-Thiazolidinedione, 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]- | |
1. Baek SJ, et al. J Biol Chem. 2003 Feb 21;278(8):5845-53.
2. Nazim UM, et al. Oncotarget. 2017 Apr 18;8(16):26819-26831.
3. Wang M, et al. Diabetes. 1999 Feb;48(2):254-60.

 
                 
                 
                 
                 
                 
                 
                 
                 
            
            
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