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Chemical Structure : Troglitazone
CAS No.: 97322-87-7
Catalog No.: PC-45908Not For Human Use, Lab Use Only.
Troglitazone (CS-045) is a PPARγ activator that has antidiabetic, anti-tumor and anti-inflammatory activities.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg (Free Sample) | $28 | In stock | |
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | Get quote |
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Troglitazone (CS-045) is a PPARγ activator that has antidiabetic, anti-tumor and anti-inflammatory activities.
Troglitazone binds to PPARγ and selectively induces the early growth response-1 gene expression.
Troglitazone inhibits biosynthesis of cholesterol in CHO cell (IC50=8 ug/ml).
Troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux.
| M.Wt | 441.5399 | |
| Formula | C24H27NO5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2,4-Thiazolidinedione, 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]- |
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1. Baek SJ, et al. J Biol Chem. 2003 Feb 21;278(8):5845-53.
2. Nazim UM, et al. Oncotarget. 2017 Apr 18;8(16):26819-26831.
3. Wang M, et al. Diabetes. 1999 Feb;48(2):254-60.
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