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Chemical Structure : IVA-337
CAS No.: 927961-18-0
Catalog No.: PC-61592Not For Human Use, Lab Use Only.
IVA-337 (Lanifibranor, IVA337)) is a potent, pan PPAR agonist with EC50 of 0.92 uM, 0.53 uM and 0.18 uM for human PPARα, PPARδ and PPARγ respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $238 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | $588 | In stock | |
| 250 mg | Get quote |
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IVA-337 (Lanifibranor, IVA337)) is a potent, pan PPAR agonist with EC50 of 0.92 uM, 0.53 uM and 0.18 uM for human PPARα, PPARδ and PPARγ respectively; reduces skin fibrosis in the mouse, and suppresses inflammation in vivo.
Steatohepatitis
Phase 2 Clinical
| M.Wt | 434.909 | |
| Formula | C19H15ClN2O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-(1-(1,3-Benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl)butanoic acid |
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1. Ruzehaji N, et al. Ann Rheum Dis. 2016 Dec;75(12):2175-2183.
2. Avouac J, et al. Ann Rheum Dis. 2017 Aug 11. pii: annrheumdis-2016-210821.
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