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Chemical Structure : Seladelpar
CAS No.: 851528-79-5
Catalog No.: PC-61150Not For Human Use, Lab Use Only.
Seladelpar (MBX-8025) is a potent, selective, orally bioavailable PPAR-delta (PPARδ) agonist with EC50 of 2 nM, displays >750-fold selective over PPAR-α.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $188 | In stock | |
| 50 mg | $288 | In stock | |
| 100 mg | $428 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Seladelpar (MBX-8025) is a potent, selective, orally bioavailable PPAR-delta (PPARδ) agonist with EC50 of 2 nM, displays >750-fold selective over PPAR-α.
Seladelpar (MBX-8025) exhibits anti-cholestatic effects and potential for the treatment of dyslipidemia, metabolic syndrome, type 2 diabetes, and non-alcoholic steatohepatitis (NASH).
| M.Wt | 444.465 | |
| Formula | C21H23F3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetic acid |
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1. Bays HE, et al. J Clin Endocrinol Metab. 2011 Sep;96(9):2889-97.
2. Jones D, et al. Lancet Gastroenterol Hepatol. 2017 Oct;2(10):716-726.
3. Choi YJ, et al. Atherosclerosis. 2012 Feb;220(2):470-6.
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