Catalog No.: PC-60333Not For Human Use, Lab Use Only.
SR1664 (SR-1664) is a potent, non-agonist PPARγ ligand that blocks the Cdk5-mediated phosphorylation in vitro (IC50=80 nM) and in vivo, without the classical agonism.
SR1664 (SR-1664) is a potent, non-agonist PPARγ ligand that blocks the Cdk5-mediated phosphorylation in vitro (IC50=80 nM) and in vivo, without the classical agonism.
SR1664 exhibits potent anti-diabetic activity while not causing the fluid retention and weight gain that are serious side effects of many of the PPARγ drugs.
SR1664 effectively improves glucose homeostasis, and does not affect bone cell mineralization in culture.
