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Chemical Structure : Fenofibrate
CAS No.: 49562-28-9
Catalog No.: PC-45176Not For Human Use, Lab Use Only.
A PPARα agonist that exhibits EC50 of 18 and 30 uM for murine and human PPARα, respectively, in a transactivation assay.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 g | $48 | In stock |
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A PPARα agonist that exhibits EC50 of 18 and 30 uM for murine and human PPARα, respectively, in a transactivation assay; reduces both LDL and VLDL levels, as well as increasing HDL levels and reduces triglyceride levels; mainly used to reduce cholesterol levels in people at risk of cardiovascular disease.
Hypercholesterolemia
Approved
| M.Wt | 360.8313 | |
| Formula | C20H21ClO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 47 mg/mL |
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| Chemical Name/SMILES |
Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester |
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1. Vu-Dac N, et al. J Biol Chem. 1998 Oct 2;273(40):25713-20.
2. Gebel T, et al. FEBS Lett. 1992 Aug 31;309(1):37-40.
3. Willson TM, et al. J Med Chem. 2000 Feb 24;43(4):527-50.
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