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Fenofibrate

Chemical Structure : Fenofibrate

CAS No.: 49562-28-9

Fenofibrate

Catalog No.: PC-45176Not For Human Use, Lab Use Only.

Fenofibrate is a PPARα agonist that exhibits EC50 of 18 and 30 uM for murine and human PPARα, respectively, in a transactivation assay.

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Biological Activity

Fenofibrate is a PPARα agonist that exhibits EC50 of 18 and 30 uM for murine and human PPARα, respectively, in a transactivation assay.
Fenofibrate reduces both LDL and VLDL levels, as well as increasing HDL levels and reduces triglyceride levels.
Fenofibrate mainly used to reduce cholesterol levels in people at risk of cardiovascular disease.

Physicochemical Properties

M.Wt 360.8313
Formula C20H21ClO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 47 mg/mL

Chemical Name/SMILES

Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester

References

1. Vu-Dac N, et al. J Biol Chem. 1998 Oct 2;273(40):25713-20.

2. Gebel T, et al. FEBS Lett. 1992 Aug 31;309(1):37-40.

3. Willson TM, et al. J Med Chem. 2000 Feb 24;43(4):527-50.

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