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Glabridin

Chemical Structure : Glabridin

CAS No.: 59870-68-7

Glabridin

Catalog No.: PC-24240Not For Human Use, Lab Use Only.

Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ with EC50 of 6.1 uM, inhibits NADPH oxidase-induced cell-mediated oxidation, exhibits antioxidant, anti-bacterial, antitumor and anti-inflammatory activities.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ with EC50 of 6.1 uM, inhibits NADPH oxidase-induced cell-mediated oxidation, exhibits antioxidant, anti-bacterial, antitumor and anti-inflammatory activities.

Physicochemical Properties

M.Wt 324.38
Formula C20H20O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-4-(8,8-Dimethyl-2,3,4,8-tetrahydropyrano[2,3-f]chromen-3-yl)benzene-1,3-diol

References

1. Rebhun JF, et al. Fitoterapia. 2015 Oct;106:55-61.

2. Tamir S, et al. Cancer Res. 2000 Oct 15;60(20):5704-9.

3. Rosenblat M, et al. J Biol Chem. 1999 May 14;274(20):13790-9.

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