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PPARα agonist A190

Chemical Structure : PPARα agonist A190

CAS No.: 2376590-40-6

PPARα agonist A190 (Compound 4u)

Catalog No.: PC-24032Not For Human Use, Lab Use Only.

PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms.

Physicochemical Properties

M.Wt 365.40
Formula C22H20FNO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((4-((4-fluorobenzyl)oxy)-3-methylbenzyl)amino)benzoic acid

References

1. Xiaozheng Dou, et al. J Med Chem. 2020 Mar 26;63(6):2854-2876.

2. Pangeni R, et al. Mol Pharm. 2025 Jan 29. doi: 10.1021/acs.molpharmaceut.4c01374.

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