PPARα agonist A190 | PPARδ agonist | Probechem Biochemicals

Chemical Structure : PPARα agonist A190

PPARα agonist A190 (Compound 4u)

Catalog No.: PC-24032Not For Human Use, Lab Use Only.

PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms.

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Biological Activity

PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms.

Physicochemical Properties

M.Wt	365.40
Formula	C22H20FNO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((4-((4-fluorobenzyl)oxy)-3-methylbenzyl)amino)benzoic acid

References

1. Xiaozheng Dou, et al. J Med Chem. 2020 Mar 26;63(6):2854-2876.

2. Pangeni R, et al. Mol Pharm. 2025 Jan 29. doi: 10.1021/acs.molpharmaceut.4c01374.

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PPARα agonist A190 (Compound 4u)

Biological Activity

Physicochemical Properties

References

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